• Human SEPT12 (Septin 12) Sandwich ELISA Kit (STJE0012102)

Human SEPT12 (Septin 12) Sandwich ELISA Kit (STJE0012102)

SKU:
STJE0012102

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.064ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This SEPT12 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: SEPTIN12
Gene ID: 124404
Uniprot ID: SEP12_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Widely expressed. Expressed in lymph node.
Post Translational Modifications
Function Filament-forming cytoskeletal GTPase. Involved in spermatogenesis. Involved in the morphogenesis of sperm heads and the elongation of sperm tails probably implicating the association with alpha- and beta-tubulins. Forms a filamentous structure with SEPTIN7, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. May play a role in cytokinesis (Potential).
Protein Name Septin-12
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Spindle
Nucleus
Cell Projection
Cilium
Flagellum
At Interphase
Forms A Filamentous Structure In The Cytoplasm
During Anaphase
Translocates To The Central Spindle Region And To The Midbody During Cytokinesis
Found In The Sperm Annulus
Colocalized With Spag4 At The Nuclear Periphery In Round Spermatids
At Sperm Neck In Elongated Spermatids And At Midpiece Regions In Ejaculated Spermatozoa
Alternative ELISA Names Septin-12 ELISA kit
SEPTIN12 ELISA kit
SEPT12 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance