Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.116ng/mL |
Detection Limit: |
0.312-20ng/mL |
Short Description: |
This SEMA4A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
SEMA4A |
Gene ID: |
64218 |
Uniprot ID: |
SEM4A_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | |
Function | Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. Regulates glutamatergic and GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner and promotes the development of excitatory synapses in a PLXNB2-dependent manner. Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. Promotes phosphorylation of TIMD2. Inhibits angiogenesis. Promotes axon growth cone collapse. Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. |
Protein Name | Semaphorin-4aSemaphorin-BSema B |
Database Links | Reactome: R-HSA-416700 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative ELISA Names | Semaphorin-4a ELISA kitSemaphorin-B ELISA kitSema B ELISA kitSEMA4A ELISA kitSEMAB ELISA kitSEMB ELISA kitUNQ783 ELISA kitPRO1317 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance