| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.063ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This SCD Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
SCD |
| Gene ID: |
6319 |
| Uniprot ID: |
SCD_HUMAN |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Detected in fetal liver, lung and brain. Highly expressed in adult adipose tissue, and at lower levels in adult brain and lung. |
| Post Translational Modifications | |
| Function | Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation. Plays an important role in body energy homeostasis. Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides. |
| Protein Name | Stearoyl-Coa DesaturaseHscd1Acyl-Coa DesaturaseDelta(9-DesaturaseDelta-9 DesaturaseFatty Acid Desaturase |
| Database Links | Reactome: R-HSA-2426168Reactome: R-HSA-75105Reactome: R-HSA-9029558 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Stearoyl-Coa Desaturase ELISA kitHscd1 ELISA kitAcyl-Coa Desaturase ELISA kitDelta(9-Desaturase ELISA kitDelta-9 Desaturase ELISA kitFatty Acid Desaturase ELISA kitSCD ELISA kitFADS5 ELISA kitSCD1 ELISA kitSCDOS ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
