Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.054ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This ROR1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
4.5 hrs |
Gene Symbol: |
ROR1 |
Gene ID: |
4919 |
Uniprot ID: |
ROR1_HUMAN |
Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. |
Post Translational Modifications | |
Function | Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. |
Protein Name | Inactive Tyrosine-Protein Kinase Transmembrane Receptor Ror1Neurotrophic Tyrosine Kinase - Receptor-Related 1 |
Database Links | Reactome: R-HSA-5140745 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionAxon |
Alternative ELISA Names | Inactive Tyrosine-Protein Kinase Transmembrane Receptor Ror1 ELISA kitNeurotrophic Tyrosine Kinase - Receptor-Related 1 ELISA kitROR1 ELISA kitNTRKR1 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance