• Human RNASEN (Ribonuclease III, Nuclear) Sandwich ELISA Kit Ready-To-Use (STJE0018305)

Human RNASEN (Ribonuclease III, Nuclear) Sandwich ELISA Kit Ready-To-Use (STJE0018305)

SKU:
STJE0018305

£481.50 - £659.50
Shipping:
Free Shipping
Current Stock:
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.126ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This RNASEN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: DROSHA
Gene ID: 29102
Uniprot ID: RNC_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Ubiquitous.
Post Translational Modifications
Function Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.
Protein Name Ribonuclease 3
Protein Drosha
Ribonuclease Iii
Rnase Iii
P241
Database Links Reactome: R-HSA-203927
Cellular Localisation Nucleus
Nucleolus
A Fraction Is Translocated To The Nucleolus During The S Phase Of The Cell Cycle
Localized In Gw Bodies (Gwbs)
Also Known As P-Bodies
Alternative ELISA Names Ribonuclease 3 ELISA kit
Protein Drosha ELISA kit
Ribonuclease Iii ELISA kit
Rnase Iii ELISA kit
P241 ELISA kit
DROSHA ELISA kit
RN3 ELISA kit
RNASE3L ELISA kit
RNASEN ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance