Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.61ng/mL |
Detection Limit: |
1.56-100ng/mL |
Short Description: |
This RNASE7 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
RNASE7 |
Gene ID: |
84659 |
Uniprot ID: |
RNAS7_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Expressed in collecting ducts in kidney, and in apical uroepithelium in bladder (at protein level). Expressed in various epithelial tissues including skin, respiratory tract, genito-urinary tract and, at a low level, in the gut. Expressed in liver, kidney, skeletal muscle and heart. |
Post Translational Modifications | |
Function | Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. |
Protein Name | Ribonuclease 7Rnase 7Skin-Derived Antimicrobial Protein 2Sap-2 |
Database Links | Reactome: R-HSA-6803157 |
Cellular Localisation | SecretedDetected In Urine |
Alternative ELISA Names | Ribonuclease 7 ELISA kitRnase 7 ELISA kitSkin-Derived Antimicrobial Protein 2 ELISA kitSap-2 ELISA kitRNASE7 ELISA kitUNQ2516 ELISA kitPRO6006 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance