• Human RIOK1 (RIO Kinase 1) Sandwich ELISA Kit Ready-To-Use (STJE0018277)

Human RIOK1 (RIO Kinase 1) Sandwich ELISA Kit Ready-To-Use (STJE0018277)

SKU:
STJE0018277

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.097ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This RIOK1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: RIOK1
Gene ID: 83732
Uniprot ID: RIOK1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. The catalytic activity regulates its dynamic association with the 40S subunit. In addition to its role in ribosomal biogenesis acts as an adapter protein by recruiting NCL/nucleolin the to PRMT5 complex for its symmetrical methylation.
Protein Name Serine/Threonine-Protein Kinase Rio1
Rio Kinase 1
Database Links Reactome: R-HSA-6791226
Cellular Localisation Cytoplasm
Cytosol
Alternative ELISA Names Serine/Threonine-Protein Kinase Rio1 ELISA kit
Rio Kinase 1 ELISA kit
RIOK1 ELISA kit
RIO1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance