Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.272ng/mL |
Detection Limit: |
0.625-40ng/mL |
Short Description: |
This RHOT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
4.5 hrs |
Gene Symbol: |
RHOT1 |
Gene ID: |
55288 |
Uniprot ID: |
MIRO1_HUMAN |
Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. |
Post Translational Modifications | Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. |
Function | Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Promotes mitochondrial fission during high calcium conditions. |
Protein Name | Mitochondrial Rho Gtpase 1Miro-1Hmiro-1Rac-Gtp-Binding Protein-Like ProteinRas Homolog Gene Family Member T1 |
Database Links | Reactome: R-HSA-5689880Reactome: R-HSA-9013425 |
Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinColocalizes With Mgarp And Rhot2 At The Mitochondria |
Alternative ELISA Names | Mitochondrial Rho Gtpase 1 ELISA kitMiro-1 ELISA kitHmiro-1 ELISA kitRac-Gtp-Binding Protein-Like Protein ELISA kitRas Homolog Gene Family Member T1 ELISA kitRHOT1 ELISA kitARHT1 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance