| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.118ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This PTP4A3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
PTP4A3 |
| Gene ID: |
11156 |
| Uniprot ID: |
TP4A3_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Mainly expressed in cardiomyocytes and skeletal muscle.also found in pancreas. Consistently overexpressed in colon cancer metastasis. |
| Post Translational Modifications | Farnesylated. Farnesylation is required for membrane targeting. |
| Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. |
| Protein Name | Protein Tyrosine Phosphatase Type Iva 3Prl-RProtein-Tyrosine Phosphatase 4a3Protein-Tyrosine Phosphatase Of Regenerating Liver 3Prl-3 |
| Database Links | |
| Cellular Localisation | Cell MembraneEarly Endosome |
| Alternative ELISA Names | Protein Tyrosine Phosphatase Type Iva 3 ELISA kitPrl-R ELISA kitProtein-Tyrosine Phosphatase 4a3 ELISA kitProtein-Tyrosine Phosphatase Of Regenerating Liver 3 ELISA kitPrl-3 ELISA kitPTP4A3 ELISA kitPRL3 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
