• Human PRB3 (Basic Salivary Proline Rich Protein 3) Sandwich ELISA Kit Ready-To-Use (STJE0018025)

Human PRB3 (Basic Salivary Proline Rich Protein 3) Sandwich ELISA Kit Ready-To-Use (STJE0018025)

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STJE0018025

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.72ng/mL
Detection Limit: 1.56-100ng/mL
Short Description: This PRB3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: PRB3Uniprot ID=PRB3_HUMAN"
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity
Post Translational Modifications The Gl-8 variant contains an interchain disulfide bond with salivary peroxidase. N- and O-glycosylated.contains about 50% carbohydrate. This is composed of highly fucosylated N-linked saccharides, the major structure is a biantennary asialosaccharide containing 2 fucose residues on one antenna and an unsubstituted terminal lactosamine sequence on the other. The Gram-negative bacterium F.nucleatum binds to carbohydrates containing unsubstituted GalBeta1,4GlcNAc residues. N-glycosylation on Asn-87 is prevalent in head and neck cancer patients. Proteolytically cleaved at the tripeptide Xaa-Pro-Gln, where Xaa in the P(3) position is mostly lysine. The endoprotease may be of microbial origin. Besides on the N-terminal of mature PRB3, pyroglutamate formation found on at least Gln-67, Gln-88, Gln-214 and Gln-295.
Function Acts as a receptor for the Gram-negative bacterium F.nucleatum.
Protein Name Basic Salivary Proline-Rich Protein 3
Parotid Salivary Glycoprotein G1
Proline-Rich Protein G1
Database Links
Cellular Localisation Secreted
Alternative ELISA Names Basic Salivary Proline-Rich Protein 3 ELISA kit
Parotid Salivary Glycoprotein G1 ELISA kit
Proline-Rich Protein G1 ELISA kit
PRB3 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance