• Human PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4) Sandwich ELISA Kit Ready-To-Use (STJE0018011)

Human PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4) Sandwich ELISA Kit Ready-To-Use (STJE0018011)

SKU:
STJE0018011

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.070ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This PPP2R4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: PTPA
Gene ID: 5524
Uniprot ID: PTPA_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Widely expressed.
Post Translational Modifications
Function PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis.the function appears to be independent from PP2A.
Protein Name Serine/Threonine-Protein Phosphatase 2a Activator
Pp2a - Subunit B' - Pr53 Isoform
Phosphotyrosyl Phosphatase Activator
Ptpa
Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit 4
Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit B'
Database Links
Cellular Localisation Cytoplasm
Nucleus
Alternative ELISA Names Serine/Threonine-Protein Phosphatase 2a Activator ELISA kit
Pp2a - Subunit B' - Pr53 Isoform ELISA kit
Phosphotyrosyl Phosphatase Activator ELISA kit
Ptpa ELISA kit
Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit 4 ELISA kit
Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit B' ELISA kit
PTPA ELISA kit
PPP2R4 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance