• Human PLXNB1 (Plexin B1) Sandwich ELISA Kit Ready-To-Use (STJE0017959)

Human PLXNB1 (Plexin B1) Sandwich ELISA Kit Ready-To-Use (STJE0017959)

SKU:
STJE0017959

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.59ng/mL
Detection Limit: 1.56-100ng/mL
Short Description: This PLXNB1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: PLXNB1
Gene ID: 5364
Uniprot ID: PLXB1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in fetal kidney, and at slightly lower levels in fetal brain, lung and liver.
Post Translational Modifications Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding. Proteolytic processing favors heterodimerization with PLXNB2 and SEMA4D binding.
Function Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
Protein Name Plexin-B1
Semaphorin Receptor Sep
Database Links Reactome: R-HSA-416482
Reactome: R-HSA-416550
Reactome: R-HSA-416572
Reactome: R-HSA-9013405
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Isoform 3: Secreted
Alternative ELISA Names Plexin-B1 ELISA kit
Semaphorin Receptor Sep ELISA kit
PLXNB1 ELISA kit
KIAA0407 ELISA kit
PLXN5 ELISA kit
SEP ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance