• Human PALLD (Palladin) Sandwich ELISA Kit Ready-To-Use (STJE0017650)

Human PALLD (Palladin) Sandwich ELISA Kit Ready-To-Use (STJE0017650)

SKU:
STJE0017650

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.051ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This PALLD Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: PALLD
Gene ID: 23022
Uniprot ID: PALLD_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Detected in both muscle and non-muscle tissues. High expression in prostate, ovary, colon, and kidney. Not detected in spleen, skeletal muscle, lung and peripheral blood lymphocytes (at protein level). Protein is overexpressed in FA6, HPAF, IMIM-PC2, SUIT-2 and PancTu-II sporadic pancreatic cancer cell lines.
Post Translational Modifications Phosphorylated predominantly on serines and, to a lesser extent, on tyrosines. Phosphorylation at Ser-1118 by PKB/AKT1 modulates cytoskeletal organization and cell motility.
Function Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci.
Protein Name Palladin
Sih002
Sarcoma Antigen Ny-Sar-77
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Junction
Focal Adhesion
Myofibril
Sarcomere
Z Line
Cell Projection
Ruffle
Podosome
Lamellipodium
Axon
Growth Cone
Localizes To Stress Fibers And Z Lines
Preferentially Expressed In The Excitatory Presynaptic Terminals
Alternative ELISA Names Palladin ELISA kit
Sih002 ELISA kit
Sarcoma Antigen Ny-Sar-77 ELISA kit
PALLD ELISA kit
KIAA0992 ELISA kit
CGI-151 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance