• Human PAFAH2 (Platelet Activating Factor Acetylhydrolase 2) Sandwich ELISA Kit (STJE0011250)

Human PAFAH2 (Platelet Activating Factor Acetylhydrolase 2) Sandwich ELISA Kit (STJE0011250)

SKU:
STJE0011250

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.105ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This PAFAH2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: PAFAH2
Gene ID: 5051
Uniprot ID: PAFA2_HUMAN
Sample Type: plasma.
Tissue Specificity Broadly expressed in different tissues, but high in B- and T-lymphocytes. In brain, expression is restricted to amygdala and frontal cortex.
Post Translational Modifications
Function Catalyzes the hydrolyze of the acetyl group at the sn-2 position of platelet-activating factor (PAF) and its analogs, leading to their inactivation. Hydrolyzes propionyl and butyroyl moieties approximately half as effectively as PAF. Also catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively. Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position.
Protein Name Platelet-Activating Factor Acetylhydrolase 2 - Cytoplasmic
Paf -Lysophospholipid Transacetylase
Paf -Sphingosine Transacetylase
Platelet-Activating Factor Acetyltransferase Pafah2
Serine-Dependent Phospholipase A2
Sd-Pla2
Hsd-Pla2
Database Links Reactome: R-HSA-418346
Cellular Localisation Cytoplasm
Membrane
Lipid-Anchor
Endoplasmic Reticulum Membrane
In Resting Cells
Localizes To Intracellular Membranes And Cytoplasm
Translocates From The Cytoplasm To Intracellular Membranes Upon Oxidative Stress
Alternative ELISA Names Platelet-Activating Factor Acetylhydrolase 2 - Cytoplasmic ELISA kit
Paf -Lysophospholipid Transacetylase ELISA kit
Paf -Sphingosine Transacetylase ELISA kit
Platelet-Activating Factor Acetyltransferase Pafah2 ELISA kit
Serine-Dependent Phospholipase A2 ELISA kit
Sd-Pla2 ELISA kit
Hsd-Pla2 ELISA kit
PAFAH2 ELISA kit
output

Information sourced from Uniprot.org

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