| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.105ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This PAFAH2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Tissue Specificity | Broadly expressed in different tissues, but high in B- and T-lymphocytes. In brain, expression is restricted to amygdala and frontal cortex. |
| Post Translational Modifications | |
| Function | Catalyzes the hydrolyze of the acetyl group at the sn-2 position of platelet-activating factor (PAF) and its analogs, leading to their inactivation. Hydrolyzes propionyl and butyroyl moieties approximately half as effectively as PAF. Also catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively. Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. |
| Protein Name | Platelet-Activating Factor Acetylhydrolase 2 - CytoplasmicPaf -Lysophospholipid TransacetylasePaf -Sphingosine TransacetylasePlatelet-Activating Factor Acetyltransferase Pafah2Serine-Dependent Phospholipase A2Sd-Pla2Hsd-Pla2 |
| Database Links | Reactome: R-HSA-418346 |
| Cellular Localisation | CytoplasmMembraneLipid-AnchorEndoplasmic Reticulum MembraneIn Resting CellsLocalizes To Intracellular Membranes And CytoplasmTranslocates From The Cytoplasm To Intracellular Membranes Upon Oxidative Stress |
| Alternative ELISA Names | Platelet-Activating Factor Acetylhydrolase 2 - Cytoplasmic ELISA kitPaf -Lysophospholipid Transacetylase ELISA kitPaf -Sphingosine Transacetylase ELISA kitPlatelet-Activating Factor Acetyltransferase Pafah2 ELISA kitSerine-Dependent Phospholipase A2 ELISA kitSd-Pla2 ELISA kitHsd-Pla2 ELISA kitPAFAH2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
