| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.062ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This PADI6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
PADI6 |
| Gene ID: |
353238 |
| Uniprot ID: |
PADI6_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Highly expressed in oocytes and weakly expressed in other somatic tissues. |
| Post Translational Modifications | Phosphorylation at Ser-10, possibly by RSK-type kinases, and Ser-446 creates binding sites for 14-3-3 proteins. |
| Function | Catalyzes the deimination of arginine residues of proteins. May be involved in cytoskeletal reorganization in the egg and early embryo. Catalyzes the deimination of arginine residues of proteins. In oocytes, is released during cortical reaction and plays a role in preimplantation cleavage and early embryonic development. May be involved in cytoskeletal reorganization in the egg and early embryo. |
| Protein Name | Protein-Arginine Deiminase Type-6Peptidyl Arginine Deiminase-Like ProteinPeptidylarginine Deiminase ViHpadviProtein-Arginine Deiminase Type Vi |
| Database Links | Reactome: R-HSA-3247509 |
| Cellular Localisation | CytoplasmNucleusCytoplasmic VesicleSecretory VesicleCortical GranulePredominantly Cytoplasmic (Oocyte Cytoplasmic Sheets)Also NuclearReleased Extracellularly During The Cortical ReactionAnd Remains Associated With The Blastomeres Surfaces As A Peripheral Membrane Protein Until The Blastocyst Stage Of Development |
| Alternative ELISA Names | Protein-Arginine Deiminase Type-6 ELISA kitPeptidyl Arginine Deiminase-Like Protein ELISA kitPeptidylarginine Deiminase Vi ELISA kitHpadvi ELISA kitProtein-Arginine Deiminase Type Vi ELISA kitPADI6 ELISA kitPAD6 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
