Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.059ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This NMU Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
NMU |
Gene ID: |
10874 |
Uniprot ID: |
NMU_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
serum, plasma or other biological fluids. |
Tissue Specificity | Expressed throughout the enteric nervous system with highest levels being found in the jejunum. |
Post Translational Modifications | |
Function | Neuromedin-U-25: Ligand for receptors NMUR1 and NMUR2. Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder. Neuromedin precursor-related peptide 33: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release although its potency is much lower than that of neuromedin precursor-related peptide 36. Neuromedin precursor-related peptide 36: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release from lactotroph cells in the pituitary gland, probably via the hypothalamic dopaminergic system. |
Protein Name | Neuromedin-U Cleaved Into - Neuromedin Precursor-Related Peptide 36Nurp36 - Neuromedin Precursor-Related Peptide 33Nurp33 - Neuromedin-U-25Nmu-25 |
Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476Reactome: R-HSA-418594 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Neuromedin-U Cleaved Into - Neuromedin Precursor-Related Peptide 36 ELISA kitNurp36 - Neuromedin Precursor-Related Peptide 33 ELISA kitNurp33 - Neuromedin-U-25 ELISA kitNmu-25 ELISA kitNMU ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance