• Human NHE3 (Sodium/Hydrogen Exchanger 3) Sandwich ELISA Kit Ready-To-Use (STJE0017355)

Human NHE3 (Sodium/Hydrogen Exchanger 3) Sandwich ELISA Kit Ready-To-Use (STJE0017355)

SKU:
STJE0017355

£481.50 - £659.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.093ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This NHE3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: SLC9A3
Gene ID: 6550
Uniprot ID: SL9A3_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylated by PKA, which inhibits activity. Phosphorylation at Ser-663 by SGK1 is associated with increased abundance at the cell membrane. Phosphorylation at Ser-718 by CSNK2A1 regulates SLC9A3 activity through the formation of multiple signaling complexes.
Function Plasma membrane Na(+)/H(+) antiporter. Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis. Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation.
Protein Name Sodium/Hydrogen Exchanger 3
Na(+/H(+ Exchanger 3
Nhe-3
Solute Carrier Family 9 Member 3
Database Links Reactome: R-HSA-425986
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Recycling Endosome Membrane
Early Endosome Membrane
In Intestinal Epithelial Cells
Localizes To The Ileal Brush Border
Phosphorylation At Ser-663 By Sgk1 Is Associated With Increased Abundance At The Cell Membrane
Angiotensin-2 Enhances Apical Expression
Alternative ELISA Names Sodium/Hydrogen Exchanger 3 ELISA kit
Na(+/H(+ Exchanger 3 ELISA kit
Nhe-3 ELISA kit
Solute Carrier Family 9 Member 3 ELISA kit
SLC9A3 ELISA kit
NHE3 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance