• Human Nectin-4 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002415)
  • Human Nectin-4 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002415)
  • Human Nectin-4 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002415)
  • Human Nectin-4 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002415)

Human Nectin-4 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002415)

SKU:
STJP002415-100

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Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Nectin-4-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications.
Conjugation: Biotin
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Endotoxin: Less than 1EU per Mu g by the LAL method.
Gene Symbol: NECTIN4
Gene ID: 81607
Uniprot ID: NECT4_HUMAN
Immunogen Region: Gly32-Val351
Immunogen: Recombinant Biotinylated Human Nectin-4 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.;It contains Gly32-Val351.
Post Translational Modifications The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17/TACE.
Function Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. (Microbial infection) Acts as a receptor for measles virus.
Protein Name Nectin-4
Ig Superfamily Receptor Lnir
Nectin Cell Adhesion Molecule 4
Poliovirus Receptor-Related Protein 4 Cleaved Into - Processed Poliovirus Receptor-Related Protein 4
Database Links Reactome: R-HSA-418990
Reactome: R-HSA-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Adherens Junction
Colocalizes With Afdn At Cadherin-Based Adherens Junctions
Processed Poliovirus Receptor-Related Protein 4: Secreted
The Secreted Form Is Found In Breast Tumor Patients
Alternative Protein Names Nectin-4 protein
Ig Superfamily Receptor Lnir protein
Nectin Cell Adhesion Molecule 4 protein
Poliovirus Receptor-Related Protein 4 Cleaved Into - Processed Poliovirus Receptor-Related Protein 4 protein
NECTIN4 protein
LNIR protein
PRR4 protein
PVRL4 protein

Information sourced from Uniprot.org

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