| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human NCR1/NKp46/CD335-C-mFc protein was developed from hek293 cells and has a target region of C-mFc. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NCR1 |
| Gene ID: |
9437 |
| Uniprot ID: |
NCTR1_HUMAN |
| Immunogen Region: |
Gln22-Asn255 |
| Immunogen: |
Recombinant Human NKp46/NCR1/CD335 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Gln22-Asn255) of Human NKp46/NCR1/CD335 fused with a mFc tag at the C-terminal. |
| Post Translational Modifications | N-glycosylated. O-glycosylated. |
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 1Lymphocyte Antigen 94 HomologNk Cell-Activating ReceptorNatural Killer Cell P46-Related ProteinNk-P46Nkp46Hnkp46Cd Antigen Cd335 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Natural Cytotoxicity Triggering Receptor 1 proteinLymphocyte Antigen 94 Homolog proteinNk Cell-Activating Receptor proteinNatural Killer Cell P46-Related Protein proteinNk-P46 proteinNkp46 proteinHnkp46 proteinCd Antigen Cd335 proteinNCR1 proteinLY94 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
