| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.119ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This NBC4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
SLC4A5 |
| Gene ID: |
57835 |
| Uniprot ID: |
S4A5_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Highest expression observed in liver, spleen and testis.moderate expression in the choroid plexus, hippocampus, cerebrum and cerebellum of brain, and in kidney cortex and kidney medulla. Also observed in heart, pancreas, muscle, lung, placenta, stomach and small intestine. Weakest expression seen in peripheral blood lymphocytes, colon, duodenum, jejunum, ileum and skeletal muscle. Isoform 3: Expressed in the brain, heart, kidney, testis, pancreas, muscle and peripheral blood leukocytes. |
| Post Translational Modifications | |
| Function | Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. |
| Protein Name | Electrogenic Sodium Bicarbonate Cotransporter 4Nbce2Solute Carrier Family 4 Member 5 |
| Database Links | Reactome: R-HSA-425381 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneExpressed In The Apical Plasma Membrane Domain Of A Subset Of Collecting Ducts In The Renal Medulla |
| Alternative ELISA Names | Electrogenic Sodium Bicarbonate Cotransporter 4 ELISA kitNbce2 ELISA kitSolute Carrier Family 4 Member 5 ELISA kitSLC4A5 ELISA kitNBC4 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
