| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
10.1pg/mL |
| Detection Limit: |
31.2-2000pg/mL |
| Short Description: |
This NAP2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
NAP1L4 |
| Gene ID: |
4676 |
| Uniprot ID: |
NP1L4_HUMAN |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Ubiquitous. Biallelically expressed in fetal and adult tissues. Highest levels in testis. |
| Post Translational Modifications | Phosphorylated at the G0/G1 boundary but it is not phosphorylated in S-phase. Phosphorylated protein remains in the cytoplasm in a complex with histones during the G0/G1 transition, whereas dephosphorylation triggers its transport into the nucleus at the G1/S-boundary. Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. |
| Function | Acts as histone chaperone in nucleosome assembly. |
| Protein Name | Nucleosome Assembly Protein 1-Like 4Nucleosome Assembly Protein 2Nap-2 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmPresent In The Cytoplasm And Excluded From The Nucleus During G0/G1 PhaseThen Relocates To The Nucleus By The Time Cells Are In S PhasePhosphorylated Form Localizes In The Cytoplasm During The G0/G1 TransitionWhereas Dephosphorylation Leads To Relocalization Into The Nucleus At The G1/S-Boundary |
| Alternative ELISA Names | Nucleosome Assembly Protein 1-Like 4 ELISA kitNucleosome Assembly Protein 2 ELISA kitNap-2 ELISA kitNAP1L4 ELISA kitNAP2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
