| Applications: |
CLIA |
| Reactivity: |
Human |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Sensitivity: |
37.5pg/mL |
| Detection Limit: |
62.5~4000pg/mL |
| Short Description: |
This human MRC1 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes. |
| Storage Instruction: |
If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual. |
| Assay Time: |
3.5h |
| Detection: |
Chemiluminescence |
| Gene Symbol: |
MRC1 |
| Gene ID: |
4360 |
| Uniprot ID: |
MRC1_HUMAN |
| Specificity: |
This kit recognizes Human MRC1 in samples. No significant cross-reactivity or interference between Human MRC1 and analogues was observed. |
| Sample Type: |
Serum, plasma and other biological fluids |
| Function | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. (Microbial infection) Interacts with Hepatitis B virus envelope protein. |
| Protein Name | Macrophage Mannose Receptor 1MmrC-Type Lectin Domain Family 13 Member DC-Type Lectin Domain Family 13 Member D-LikeHuman Mannose ReceptorHmrMacrophage Mannose Receptor 1-Like Protein 1Cd Antigen Cd206 |
| Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-9637628 |
| Cellular Localisation | Endosome MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative CLIA Names | Macrophage Mannose Receptor 1 CLIA kitMmr CLIA kitC-Type Lectin Domain Family 13 Member D CLIA kitC-Type Lectin Domain Family 13 Member D-Like CLIA kitHuman Mannose Receptor CLIA kitHmr CLIA kitMacrophage Mannose Receptor 1-Like Protein 1 CLIA kitCd Antigen Cd206 CLIA kitMRC1 CLIA kitCLEC13D CLIA kitCLEC13DL CLIA kitMRC1L1 CLIA kit |
| Specificity | This kit recognizes Human MRC1 in samples. No significant cross-reactivity or interference between Human MRC1 and analogues was observed. |
| Reproducibility | Both intra-CV and inter-CV are |
Information sourced from Uniprot.org
| Item | Specifications | Storage |
| Micro CLIA Plate (Dismountable) | 96T: 8 wells ×12 strips strips | -20℃, 6 months |
| Reference Standard | 96T: 2 vials 48T: 1 vial | -20℃, 6 months |
| Concentrated Biotinylated Detection Ab (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃, 6 months |
| Concentrated HRP Conjugate (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃ (Protect from light), 6 months |
| Reference Standard & Sample Diluent | 1 vial, 20 mL | 2-8°C, 6 months |
| Biotinylated Detection Ab Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
| HRP Conjugate Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
| Concentrated Wash Buffer (25×) | 1 vial, 30 mL | 2-8°C, 6 months |
| Substrate Reagent A | 1 vial, 5 mL | 2-8℃ (Protect from light) |
| Substrate Reagent B | 1 vial, 5 mL | 2-8℃ (Protect from light) |
| Plate Sealer | 5 pieces | |
| Manual | 1 copy | |
| Certificate of Analysis | 1 copy | |
| Sample Type | Range (%) | Average Recovery (%) |
| Serum(n=8) | 87-98 | 93 |
| EDTA plasma(n=8) | 97-112 | 105 |
| Cell culture media(n=8) | 91-103 | 97 |
| | Intra-assay Precision | Intra-assay Precision | Intra-assay Precision | Inter-assay Precision | Inter-assay Precision | Inter-assay Precision |
| Sample | 1.00 | 2.00 | 3.00 | 1.00 | 2.00 | 3.00 |
| n | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 |
| Mean (pg/mL) | 207.64 | 402.37 | 1905.92 | 194.26 | 411.68 | 1807.56 |
| Standard deviation | 20.87 | 35.69 | 114.55 | 18.42 | 45.37 | 157.26 |
| CV (%) | 10.05 | 8.87 | 6.01 | 9.48 | 11.02 | 8.70 |
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
