• Human MPIF1 (Myeloid Progenitor Inhibitory Factor 1) Sandwich ELISA Kit (STJE0010709)

Human MPIF1 (Myeloid Progenitor Inhibitory Factor 1) Sandwich ELISA Kit (STJE0010709)

SKU:
STJE0010709

Shipping:
Free Shipping
Current Stock:
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 5.4pg/mL
Detection Limit: 15.6-1000pg/mL
Short Description: This MPIF1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: CCL23
Gene ID: 6368
Uniprot ID: CCL23_HUMAN
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are found in high levels in synovial fluids from rheumatoid patients.
Post Translational Modifications The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms, CCL23(19-99), CCL23(22-99), CCL23(27-99) and CCL23(30-99) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro.
Function Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23.
Protein Name C-C Motif Chemokine 23
Ck-Beta-8
Ckb-8
Macrophage Inflammatory Protein 3
Mip-3
Myeloid Progenitor Inhibitory Factor 1
Mpif-1
Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99
Database Links Reactome: R-HSA-416476 P55773-2
Reactome: R-HSA-418594 P55773-2
Reactome: R-HSA-444473 P55773-2
Cellular Localisation Secreted
Alternative ELISA Names C-C Motif Chemokine 23 ELISA kit
Ck-Beta-8 ELISA kit
Ckb-8 ELISA kit
Macrophage Inflammatory Protein 3 ELISA kit
Mip-3 ELISA kit
Myeloid Progenitor Inhibitory Factor 1 ELISA kit
Mpif-1 ELISA kit
Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99 ELISA kit
CCL23 ELISA kit
MIP3 ELISA kit
MPIF1 ELISA kit
SCYA23 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance