| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.064ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This MOSC1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
MTARC1 |
| Gene ID: |
64757 |
| Uniprot ID: |
MARC1_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction. |
| Protein Name | Mitochondrial Amidoxime-Reducing Component 1Marc1Molybdenum Cofactor Sulfurase C-Terminal Domain-Containing Protein 1Mosc Domain-Containing Protein 1Moco Sulfurase C-Terminal Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Ii Membrane ProteinMembraneLipid-AnchorMitochondrial Import Is Mediated By Aa 1-40 And Requires Atp |
| Alternative ELISA Names | Mitochondrial Amidoxime-Reducing Component 1 ELISA kitMarc1 ELISA kitMolybdenum Cofactor Sulfurase C-Terminal Domain-Containing Protein 1 ELISA kitMosc Domain-Containing Protein 1 ELISA kitMoco Sulfurase C-Terminal Domain-Containing Protein 1 ELISA kitMTARC1 ELISA kitMARC1 ELISA kitMOSC1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
