• Human MMRN1 (Multimerin-1) CLIA Kit (STJC0000316)

Human MMRN1 (Multimerin-1) CLIA Kit (STJC0000316)

SKU:
STJC0000316

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Applications: CLIA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity: 9.38pg/mL
Detection Limit: 15.63~1000pg/mL
Short Description: This human MMRN1 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Storage Instruction: If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time: 3.5h
Detection: Chemiluminescence
Gene Symbol: MMRN1
Gene ID: 22915
Uniprot ID: MMRN1_HUMAN
Specificity: This kit recognizes Human MMRN1 in samples. No significant cross-reactivity or interference between Human MMRN1 and analogues was observed.
Sample Type: Serum, plasma and other biological fluids
Tissue Specificity Synthesized by endothelial cells and megakaryocytes. Stored in platelet alpha granules and endothelial cell Weibel-Palade bodies, following activation of these cells, it is released and attached to megakaryocytes, platelets, endothelium and subendothelium of blood vessels. Not found in plasma. Found in vascular tissues such as placenta, lung, and liver.
Post Translational Modifications The N-terminus is blocked. Extensively N-glycosylated.
Function Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein.
Protein Name Multimerin-1
Emilin-4
Elastin Microfibril Interface Located Protein 4
Elastin Microfibril Interfacer 4
Endothelial Cell Multimerin Cleaved Into - Platelet Glycoprotein Ia* - 155 Kda Platelet Multimerin
P-155
P155
Database Links Reactome: R-HSA-114608
Cellular Localisation Secreted
Alternative CLIA Names Multimerin-1 CLIA kit
Emilin-4 CLIA kit
Elastin Microfibril Interface Located Protein 4 CLIA kit
Elastin Microfibril Interfacer 4 CLIA kit
Endothelial Cell Multimerin Cleaved Into - Platelet Glycoprotein Ia* - 155 Kda Platelet Multimerin CLIA kit
P-155 CLIA kit
P155 CLIA kit
MMRN1 CLIA kit
ECM CLIA kit
EMILIN4 CLIA kit
GPIA* CLIA kit
MMRN CLIA kit
Specificity This kit recognizes Human MMRN1 in samples. No significant cross-reactivity or interference between Human MMRN1 and analogues was observed.
Reproducibility Both intra-CV and inter-CV are

Information sourced from Uniprot.org


Item Specifications Storage
Micro CLIA Plate (Dismountable) 96T: 8 wells ×12 strips strips -20℃, 6 months
Reference Standard 96T: 2 vials 48T: 1 vial -20℃, 6 months
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL 60 μL -20℃, 6 months
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL 60 μL -20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL 2-8°C, 6 months
HRP Conjugate Diluent 1 vial, 14 mL 2-8°C, 6 months
Concentrated Wash Buffer (25×) 1 vial, 30 mL 2-8°C, 6 months
Substrate Reagent A 1 vial, 5 mL 2-8℃ (Protect from light)
Substrate Reagent B 1 vial, 5 mL 2-8℃ (Protect from light)
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 98-115 105
EDTA plasma(n=8) 101-115 107
Cell culture media(n=8) 86-99 91

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision
Sample 1.00 2.00 3.00 1.00 2.00 3.00
n 20.00 20.00 20.00 20.00 20.00 20.00
Mean (pg/mL) 47.41 126.23 434.08 47.72 116.03 455.70
Standard deviation 5.12 14.52 43.89 6.14 9.27 34.41
CV (%) 10.80 11.50 10.11 12.87 7.99 7.55
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance