• Human MMP16 (Matrix Metalloproteinase 16) Sandwich ELISA Kit (STJE0010660)

Human MMP16 (Matrix Metalloproteinase 16) Sandwich ELISA Kit (STJE0010660)

SKU:
STJE0010660

£317.50 - £605.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.063ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This MMP16 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: MMP16
Gene ID: 4325
Uniprot ID: MMP16_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed in heart, brain, placenta, ovary and small intestine. Isoform Short is found in the ovary.
Post Translational Modifications The precursor is cleaved by a furin endopeptidase.
Function Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Protein Name Matrix Metalloproteinase-16
Mmp-16
Mmp-X2
Membrane-Type Matrix Metalloproteinase 3
Mt-Mmp 3
Mtmmp3
Membrane-Type-3 Matrix Metalloproteinase
Mt3-Mmp
Mt3mmp
Database Links Reactome: R-HSA-1592389
Cellular Localisation Isoform Long: Cell Membrane
Single-Pass Type I Membrane Protein
Extracellular Side
Localized At The Cell Surface Of Melanoma Cells
Isoform Short: Secreted
Extracellular Space
Extracellular Matrix
Cell Surface
Alternative ELISA Names Matrix Metalloproteinase-16 ELISA kit
Mmp-16 ELISA kit
Mmp-X2 ELISA kit
Membrane-Type Matrix Metalloproteinase 3 ELISA kit
Mt-Mmp 3 ELISA kit
Mtmmp3 ELISA kit
Membrane-Type-3 Matrix Metalloproteinase ELISA kit
Mt3-Mmp ELISA kit
Mt3mmp ELISA kit
MMP16 ELISA kit
C8orf57 ELISA kit
MMPX2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance