| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.063ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This MMP16 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
MMP16 |
| Gene ID: |
4325 |
| Uniprot ID: |
MMP16_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in heart, brain, placenta, ovary and small intestine. Isoform Short is found in the ovary. |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells. |
| Protein Name | Matrix Metalloproteinase-16Mmp-16Mmp-X2Membrane-Type Matrix Metalloproteinase 3Mt-Mmp 3Mtmmp3Membrane-Type-3 Matrix MetalloproteinaseMt3-MmpMt3mmp |
| Database Links | Reactome: R-HSA-1592389 |
| Cellular Localisation | Isoform Long: Cell MembraneSingle-Pass Type I Membrane ProteinExtracellular SideLocalized At The Cell Surface Of Melanoma CellsIsoform Short: SecretedExtracellular SpaceExtracellular MatrixCell Surface |
| Alternative ELISA Names | Matrix Metalloproteinase-16 ELISA kitMmp-16 ELISA kitMmp-X2 ELISA kitMembrane-Type Matrix Metalloproteinase 3 ELISA kitMt-Mmp 3 ELISA kitMtmmp3 ELISA kitMembrane-Type-3 Matrix Metalloproteinase ELISA kitMt3-Mmp ELISA kitMt3mmp ELISA kitMMP16 ELISA kitC8orf57 ELISA kitMMPX2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
