Human MIF (MIF) Sandwich ELISA Kit (STJE0000060)

SKU:
STJE0000060-96

£437.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 7.6 pg/mL
Detection Limit: 156-1000 pg/mL
Short Description: This MIF Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Conjugation: Biotin
Storage Instruction: Unopened kits can be stored at 2-8°C for 1 year, and opened products must be used within 1 month.
Assay Time: 4 hours
Detection: Colorimetric
Gene Symbol: MIF
Gene ID: 4282
Uniprot ID: MIF_HUMAN
Sample Type: serum, plasma and cell culture supernates
Tissue Specificity
Post Translational Modifications
Function Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Protein Name Macrophage Migration Inhibitory Factor
Mif
Glycosylation-Inhibiting Factor
Gif
L-Dopachrome Isomerase
L-Dopachrome Tautomerase
Phenylpyruvate Tautomerase
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Reactome: R-HSA-8950505
Cellular Localisation Secreted
Cytoplasm
Does Not Have A Cleavable Signal Sequence And Is Secreted Via A Specialized
Non-Classical Pathway
Secreted By Macrophages Upon Stimulation By Bacterial Lipopolysaccharide (Lps)
Or By M
Tuberculosis Antigens
Alternative ELISA Names Macrophage Migration Inhibitory Factor ELISA kit
Mif ELISA kit
Glycosylation-Inhibiting Factor ELISA kit
Gif ELISA kit
L-Dopachrome Isomerase ELISA kit
L-Dopachrome Tautomerase ELISA kit
Phenylpyruvate Tautomerase ELISA kit
MIF ELISA kit
GLIF ELISA kit
MMIF ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance