Human MAX protein (Recombinant) (N-GST) (STJP005017)

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STJP005017
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MAX-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MAX
Gene ID: 4149
Uniprot ID: MAX_HUMAN
Immunogen Region: Ser2-Ser160
Immunogen: Homo sapiens (Human)
Post Translational Modifications Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes.
Function Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CACGATG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements.
Protein Name Protein Max
Class D Basic Helix-Loop-Helix Protein 4
Bhlhd4
Myc-Associated Factor X
Database Links Reactome: R-HSA-1362277
Reactome: R-HSA-69202
Reactome: R-HSA-69656
Reactome: R-HSA-8953750
Cellular Localisation Nucleus
Cell Projection
Dendrite
Alternative Protein Names Protein Max protein
Class D Basic Helix-Loop-Helix Protein 4 protein
Bhlhd4 protein
Myc-Associated Factor X protein
MAX protein
BHLHD4 protein

Information sourced from Uniprot.org

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