Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.127ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This LRRFIP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | LRRFIP1 |
Gene ID: | 9208 |
Uniprot ID: | LRRF1_HUMAN |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Ubiquitously expressed. |
Post Translational Modifications | |
Function | Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. |
Protein Name | Leucine-Rich Repeat Flightless-Interacting Protein 1 Lrr Flii-Interacting Protein 1 Gc-Binding Factor 2 Tar Rna-Interacting Protein |
Database Links | Reactome: R-HSA-1839117 Reactome: R-HSA-3134973 Reactome: R-HSA-5655302 |
Cellular Localisation | Nucleus Cytoplasm |
Alternative ELISA Names | Leucine-Rich Repeat Flightless-Interacting Protein 1 ELISA kit Lrr Flii-Interacting Protein 1 ELISA kit Gc-Binding Factor 2 ELISA kit Tar Rna-Interacting Protein ELISA kit LRRFIP1 ELISA kit GCF2 ELISA kit TRIP ELISA kit |
output |
Information sourced from Uniprot.org