| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.061ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This LDB1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
LDB1 |
| Gene ID: |
8861 |
| Uniprot ID: |
LDB1_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in a wide range of adult tissues including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes. |
| Post Translational Modifications | Ubiquitinated by RLIM/RNF12, leading to its degradation by the proteasome. |
| Function | Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state. |
| Protein Name | Lim Domain-Binding Protein 1Ldb-1Carboxyl-Terminal Lim Domain-Binding Protein 2Clim-2Lim Domain-Binding Factor Clim2Hldb1Nuclear Lim Interactor |
| Database Links | Reactome: R-HSA-8939236Reactome: R-HSA-9010553Reactome: R-HSA-9733709Reactome: R-HSA-9752946 |
| Cellular Localisation | NucleusColocalizes With Slk At Leading Edges |
| Alternative ELISA Names | Lim Domain-Binding Protein 1 ELISA kitLdb-1 ELISA kitCarboxyl-Terminal Lim Domain-Binding Protein 2 ELISA kitClim-2 ELISA kitLim Domain-Binding Factor Clim2 ELISA kitHldb1 ELISA kitNuclear Lim Interactor ELISA kitLDB1 ELISA kitCLIM2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
