| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
6.1pg/mL |
| Detection Limit: |
15.6-1000pg/mL |
| Short Description: |
This LAMa3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
LAMA3 |
| Gene ID: |
3909 |
| Uniprot ID: |
LAMA3_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Skin.respiratory, urinary, and digestive epithelia and in other specialized tissues with prominent secretory or protective functions. Epithelial basement membrane, and epithelial cell tongue that migrates into a wound bed. A differential and focal expression of the subunit alpha-3 is observed in the CNS. |
| Post Translational Modifications | |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes. |
| Protein Name | Laminin Subunit Alpha-3Epiligrin 170 Kda SubunitE170Epiligrin Subunit AlphaKalinin Subunit AlphaLaminin-5 Subunit AlphaLaminin-6 Subunit AlphaLaminin-7 Subunit AlphaNicein Subunit Alpha |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-2022090Reactome: R-HSA-2214320Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-446107Reactome: R-HSA-8874081 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative ELISA Names | Laminin Subunit Alpha-3 ELISA kitEpiligrin 170 Kda Subunit ELISA kitE170 ELISA kitEpiligrin Subunit Alpha ELISA kitKalinin Subunit Alpha ELISA kitLaminin-5 Subunit Alpha ELISA kitLaminin-6 Subunit Alpha ELISA kitLaminin-7 Subunit Alpha ELISA kitNicein Subunit Alpha ELISA kitLAMA3 ELISA kitLAMNA ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
