• Human KRT2 (Keratin 2) Sandwich ELISA Kit (STJE0010229)

Human KRT2 (Keratin 2) Sandwich ELISA Kit (STJE0010229)

SKU:
STJE0010229

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.059ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This KRT2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: KRT2
Gene ID: 3849
Uniprot ID: K22E_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed in the upper spinous and granular suprabasal layers of normal adult epidermal tissues from most body sites including thigh, breast nipple, foot sole, penile shaft and axilla. Not present in foreskin, squamous metaplasias and carcinomas. Expression in hypertrophic and keloid scars begins in the deepest suprabasal layer. Weakly expressed in normal gingiva and tongue, however expression is induced in benign keratoses of lingual mucosa and in mild-to-moderate oral dysplasia with orthokeratinization.
Post Translational Modifications
Function Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins. Plays a role in the establishment of the epidermal barrier on plantar skin.
Protein Name Keratin - Type Ii Cytoskeletal 2 Epidermal
Cytokeratin-2e
Ck-2e
Epithelial Keratin-2e
Keratin-2 Epidermis
Keratin-2e
K2e
Type-Ii Keratin Kb2
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cytoplasm
Alternative ELISA Names Keratin - Type Ii Cytoskeletal 2 Epidermal ELISA kit
Cytokeratin-2e ELISA kit
Ck-2e ELISA kit
Epithelial Keratin-2e ELISA kit
Keratin-2 Epidermis ELISA kit
Keratin-2e ELISA kit
K2e ELISA kit
Type-Ii Keratin Kb2 ELISA kit
KRT2 ELISA kit
KRT2A ELISA kit
KRT2E ELISA kit
output

Information sourced from Uniprot.org

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