Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.118ng/mL |
Detection Limit: |
0.312-20ng/mL |
Short Description: |
This KIF5A Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
4.5 hrs |
Gene Symbol: |
KIF5A |
Gene ID: |
3798 |
Uniprot ID: |
KIF5A_HUMAN |
Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Distributed throughout the CNS but is highly enriched in subsets of neurons. |
Post Translational Modifications | |
Function | Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. |
Protein Name | Kinesin Heavy Chain Isoform 5aKinesin Heavy Chain Neuron-Specific 1Neuronal Kinesin Heavy ChainNkhc |
Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-264876Reactome: R-HSA-5625970Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
Cellular Localisation | CytoplasmPerinuclear RegionCytoskeletonPerikaryonConcentrated In The Cell Body Of The NeuronsParticularly In The Perinuclear Region |
Alternative ELISA Names | Kinesin Heavy Chain Isoform 5a ELISA kitKinesin Heavy Chain Neuron-Specific 1 ELISA kitNeuronal Kinesin Heavy Chain ELISA kitNkhc ELISA kitKIF5A ELISA kitNKHC1 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance