| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications. |
| Conjugation: | Biotin |
| Formulation: | Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
| Dilution Range: | Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
| Storage Instruction: | The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
| Gene Symbol: | ITGAV |
| Gene ID: | 3685 |
| Uniprot ID: | ITAV_HUMAN |
| Immunogen Region: | Phe31-Val992 (ITGAV) & Gly22-Asn707 (ITGB6) |
| Immunogen: | DNA sequence encoding Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
| Protein Name | Integrin Alpha-V Vitronectin Receptor Vitronectin Receptor Subunit Alpha Cd Antigen Cd51 Cleaved Into - Integrin Alpha-V Heavy Chain - Integrin Alpha-V Light Chain |
| Database Links | Reactome: R-HSA-1236973 Reactome: R-HSA-1566948 Reactome: R-HSA-210990 Reactome: R-HSA-2129379 Reactome: R-HSA-216083 Reactome: R-HSA-2173789 Reactome: R-HSA-3000157 Reactome: R-HSA-3000170 Reactome: R-HSA-3000178 Reactome: R-HSA-4420097 Reactome: R-HSA-445144 Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Cell Junction Focal Adhesion |
| Alternative Protein Names | Integrin Alpha-V protein Vitronectin Receptor protein Vitronectin Receptor Subunit Alpha protein Cd Antigen Cd51 Cleaved Into - Integrin Alpha-V Heavy Chain - Integrin Alpha-V Light Chain protein ITGAV protein MSK8 protein VNRA protein VTNR protein |
Information sourced from Uniprot.org