• Human IL35 (Interleukin 35) Sandwich ELISA Kit Ready-To-Use (STJE0016312)

Human IL35 (Interleukin 35) Sandwich ELISA Kit Ready-To-Use (STJE0016312)

SKU:
STJE0016312

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 5.6pg/mL
Detection Limit: 15.6-1000pg/mL
Short Description: This IL35 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: EBI3
Gene ID: 10148
Uniprot ID: IL27B_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
Protein Name Interleukin-27 Subunit Beta
Il-27 Subunit Beta
Il-27b
Epstein-Barr Virus-Induced Gene 3 Protein
Ebv-Induced Gene 3 Protein
Database Links Reactome: R-HSA-8984722
Reactome: R-HSA-9020956
Cellular Localisation Secreted
Alternative ELISA Names Interleukin-27 Subunit Beta ELISA kit
Il-27 Subunit Beta ELISA kit
Il-27b ELISA kit
Epstein-Barr Virus-Induced Gene 3 Protein ELISA kit
Ebv-Induced Gene 3 Protein ELISA kit
EBI3 ELISA kit
IL27B ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance