Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.051ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This IL18RAP Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
IL18RAP |
Gene ID: |
8807 |
Uniprot ID: |
I18RA_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
tissue homogenates or other biological fluids. |
Tissue Specificity | Detected in adrenal gland, bone marrow, brain, fetal brain, fetal liver, heart, kidney, lung, liver, peripheral blood leukocytes, placenta, prostate, salivary gland, skeletal muscle, spinal cord, testis, thymus, thyroid, trachea and uterus. Strongly expressed in peripheral blood leukocytes and spleen and, to a lesser extent, in colon. Specifically coexpressed with IL18R1 in T-helper 1 (Th1)cells. |
Post Translational Modifications | N-glycosylated. |
Function | Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable). |
Protein Name | Interleukin-18 Receptor Accessory ProteinIl-18 Receptor Accessory ProteinIl-18racpAccessory Protein-LikeAcplCd218 Antigen-Like Family Member BCdw218bIl-1r Accessory Protein-LikeIl-1racplInterleukin-1 Receptor 7Il-1r-7Il-1r7Interleukin-18 Receptor Accessory Protein-LikeInterleukin-18 Receptor BetaIl-18r-BetaIl-18rbetaCd Antigen Cd218b |
Database Links | Reactome: R-HSA-9012546 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative ELISA Names | Interleukin-18 Receptor Accessory Protein ELISA kitIl-18 Receptor Accessory Protein ELISA kitIl-18racp ELISA kitAccessory Protein-Like ELISA kitAcpl ELISA kitCd218 Antigen-Like Family Member B ELISA kitCdw218b ELISA kitIl-1r Accessory Protein-Like ELISA kitIl-1racpl ELISA kitInterleukin-1 Receptor 7 ELISA kitIl-1r-7 ELISA kitIl-1r7 ELISA kitInterleukin-18 Receptor Accessory Protein-Like ELISA kitInterleukin-18 Receptor Beta ELISA kitIl-18r-Beta ELISA kitIl-18rbeta ELISA kitCd Antigen Cd218b ELISA kitIL18RAP ELISA kitIL1R7 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance