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Human IGFBP1 (Insulin Like Growth Factor Binding Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0006882)

Human IGFBP1 (Insulin Like Growth Factor Binding Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0006882)

Human IGFBP1 (Insulin Like Growth Factor Binding Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0006882)

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STJE0006882

£293.50 - £391.50

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.061ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This IGFBP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	IGFBP1
Gene ID:	3484
Uniprot ID:	IBP1_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Phosphorylated.probably by casein kinase II. Phosphorylation alters the affinity of the protein for IGFs. In amniotic fluid, the unmodified protein is the most abundant form, while mono-, bi-, tri- and tetraphosphorylated forms are present in decreasing amounts. The phosphorylation state may influence the propensity to proteolysis.
Function	IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
Protein Name	Insulin-Like Growth Factor-Binding Protein 1 Ibp-1 Igf-Binding Protein 1 Igfbp-1 Placental Protein 12 Pp12
Database Links	Reactome: R-HSA-380994 Reactome: R-HSA-381426 Reactome: R-HSA-8957275 Reactome: R-HSA-9615017
Cellular Localisation	Secreted
Alternative ELISA Names	Insulin-Like Growth Factor-Binding Protein 1 ELISA kit Ibp-1 ELISA kit Igf-Binding Protein 1 ELISA kit Igfbp-1 ELISA kit Placental Protein 12 ELISA kit Pp12 ELISA kit IGFBP1 ELISA kit IBP1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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