| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human IFI30-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Lyophilized from sterile PBS, pH 7.4 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IFI30 |
| Gene ID: |
10437 |
| Uniprot ID: |
GILT_HUMAN |
| Immunogen Region: |
Met1-Lys243 |
| Immunogen: |
Recombinant Human IFI30 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Lys243) of human IFI30 (Accession #NP_006323.2) fused with a 6×His tag at the C-terminus. |
| Function | Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds. Facilitates also MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation. |
| Protein Name | Gamma-Interferon-Inducible Lysosomal Thiol ReductaseGamma-Interferon-Inducible Protein Ip-30Legumaturain |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-877300 |
| Cellular Localisation | SecretedLysosome |
| Alternative Protein Names | Gamma-Interferon-Inducible Lysosomal Thiol Reductase proteinGamma-Interferon-Inducible Protein Ip-30 proteinLegumaturain proteinIFI30 proteinGILT proteinIP30 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
