| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
1.26ng/mL |
| Detection Limit: |
3.12-200ng/mL |
| Short Description: |
This IDH1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
IDH1 |
| Gene ID: |
3417 |
| Uniprot ID: |
IDHC_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Acetylation at Lys-374 dramatically reduces catalytic activity. |
| Function | Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase. Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways. May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency. |
| Protein Name | Isocitrate Dehydrogenase Nadp CytoplasmicIdhIdh1Cytosolic Nadp-Isocitrate DehydrogenaseIdpcNadp(+-Specific IcdhOxalosuccinate Decarboxylase |
| Database Links | Reactome: R-HSA-2978092Reactome: R-HSA-389542Reactome: R-HSA-6798695Reactome: R-HSA-9033241Reactome: R-HSA-9818025 |
| Cellular Localisation | CytoplasmCytosolPeroxisome |
| Alternative ELISA Names | Isocitrate Dehydrogenase Nadp Cytoplasmic ELISA kitIdh ELISA kitIdh1 ELISA kitCytosolic Nadp-Isocitrate Dehydrogenase ELISA kitIdpc ELISA kitNadp(+-Specific Icdh ELISA kitOxalosuccinate Decarboxylase ELISA kitIDH1 ELISA kitPICD ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
