Host: | Rabbit/Rabbit |
Applications: | ELISA |
Reactivity: | Human |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description : | This ICAM-3/CD50 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
Conjugation: | Unconjugated/Biotin |
Formulation: | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
Purification: | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
Concentration: | 0.5 mg/mL |
Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
Determination Method: | Colormetric |
Gene Symbol: | ICAM3 |
Gene ID: | 3385 |
Uniprot ID: | ICAM3_HUMAN |
Immunogen: | Capture immunogen: Recombinant Human ICAM-3/CD50 protien.Detection Immunogen: Recombinant Human ICAM-3/CD50 protien. |
Sample Type: | Serum, plasma and other biological fluids |
Post Translational Modifications | Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues. N-glycosylated.glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains. |
Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages. |
Protein Name | Intercellular Adhesion Molecule 3Icam-3Cdw50Icam-RCd Antigen Cd50 |
Database Links | Reactome: R-HSA-198933Reactome: R-HSA-216083Reactome: R-HSA-5621575 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Pair Names | Intercellular Adhesion Molecule 3 antibody pairIcam-3 antibody pairCdw50 antibody pairIcam-R antibody pairCd Antigen Cd50 antibody pairICAM3 antibody pair |
Information sourced from Uniprot.org