• Human HSD17b3 (17-Beta-Hydroxysteroid Dehydrogenase Type 3) Sandwich ELISA Kit (STJE0009532)

Human HSD17b3 (17-Beta-Hydroxysteroid Dehydrogenase Type 3) Sandwich ELISA Kit (STJE0009532)

SKU:
STJE0009532

£329.50 - £631.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 6.4pg/mL
Detection Limit: 15.6-1000pg/mL
Short Description: This HSD17b3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: HSD17B3
Gene ID: 3293
Uniprot ID: DHB3_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Testis.
Post Translational Modifications
Function Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids. Favors the reduction of androstenedione to testosterone. Testosterone is the key androgen driving male development and function. Uses NADPH while the two other EDH17B enzymes use NADH. Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17. Can reduce 11-ketoandrostenedione as well as 11beta-hydroxyandrostenedione at C-17 to the respective testosterone forms.
Protein Name 17-Beta-Hydroxysteroid Dehydrogenase Type 3
17-Beta-Hsd 3
Estradiol 17-Beta-Dehydrogenase 2
Short Chain Dehydrogenase/Reductase Family 12c Member 2
Testicular 17-Beta-Hydroxysteroid Dehydrogenase
Testosterone 17-Beta-Dehydrogenase 3
Database Links Reactome: R-HSA-193048
Reactome: R-HSA-75876
Cellular Localisation Endoplasmic Reticulum
Alternative ELISA Names 17-Beta-Hydroxysteroid Dehydrogenase Type 3 ELISA kit
17-Beta-Hsd 3 ELISA kit
Estradiol 17-Beta-Dehydrogenase 2 ELISA kit
Short Chain Dehydrogenase/Reductase Family 12c Member 2 ELISA kit
Testicular 17-Beta-Hydroxysteroid Dehydrogenase ELISA kit
Testosterone 17-Beta-Dehydrogenase 3 ELISA kit
HSD17B3 ELISA kit
EDH17B3 ELISA kit
SDR12C2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance