Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human HSD17B13-C-Flag protein was developed from hek293 cells and has a target region of C-Flag. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HSD17B13 |
Gene ID: |
345275 |
Uniprot ID: |
DHB13_HUMAN |
Immunogen Region: |
Met1-Lys300 |
Immunogen: |
Recombinant Human HSD17B13 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Lys300) of Human HSD17B13 (Accession #NP_835236.2) fused with Flag tag at the C-terminus. |
Function | Plays a pivotal role in hepatic lipid metabolism. In vitro, it catalyzes the oxidation of a variety of lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4. Isoform 2: Has retinol/retinal dehydrogenase activity in vitro. Isoform 1: Does not have retinol/retinal dehydrogenase activity in vitro. |
Protein Name | 17-Beta-Hydroxysteroid Dehydrogenase 1317-Beta-Hsd 13Hepatic Retinol/Retinal DehydrogenaseShort Chain Dehydrogenase/Reductase Family 16c Member 3Short-Chain Dehydrogenase/Reductase 9 |
Database Links | Reactome: R-HSA-8964572 |
Cellular Localisation | Isoform 2: Lipid DropletEndoplasmic ReticulumRedistributed From The Endoplasmic Reticulum To Lipids Droplets In The Cell Upon Induction Of Lipids Droplet FormationIsoform 1: CytoplasmDoes Not Localize To Lipid Droplets |
Alternative Protein Names | 17-Beta-Hydroxysteroid Dehydrogenase 13 protein17-Beta-Hsd 13 proteinHepatic Retinol/Retinal Dehydrogenase proteinShort Chain Dehydrogenase/Reductase Family 16c Member 3 proteinShort-Chain Dehydrogenase/Reductase 9 proteinHSD17B13 proteinSCDR9 proteinSDR16C3 proteinHMFN0376 proteinUNQ497 proteinPRO1014 protein |
Information sourced from Uniprot.org
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