| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.052ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This HS2ST1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Hs2st1 |
| Gene ID: |
23908 |
| Uniprot ID: |
HS2ST_MOUSE |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Widely expressed. Expressed at higher level in lung and brain. Weakly expressed in spleen. |
| Post Translational Modifications | N-glycosylated. |
| Function | Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Required for metanephric development of kidney formation, suggesting that 2-O-sulfation within HS is essential for signaling between ureteric bud and metanephric mesenchyme. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues. |
| Protein Name | Heparan Sulfate 2-O-Sulfotransferase 12-O-Sulfotransferase2-Ost2ost |
| Database Links | Reactome: R-MMU-2022928 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative ELISA Names | Heparan Sulfate 2-O-Sulfotransferase 1 ELISA kit2-O-Sulfotransferase ELISA kit2-Ost ELISA kit2ost ELISA kitHs2st1 ELISA kitHs2st ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
