Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.052ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This HEMGN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
HEMGN |
Gene ID: |
55363 |
Uniprot ID: |
HEMGN_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
tissue homogenates or other biological fluids. |
Tissue Specificity | Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level). Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. |
Post Translational Modifications | |
Function | Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB). |
Protein Name | HemogenErythroid Differentiation-Associated Gene ProteinEdag-1Hemopoietic Gene ProteinNegative Differentiation Regulator Protein |
Database Links | |
Cellular Localisation | Nucleus |
Alternative ELISA Names | Hemogen ELISA kitErythroid Differentiation-Associated Gene Protein ELISA kitEdag-1 ELISA kitHemopoietic Gene Protein ELISA kitNegative Differentiation Regulator Protein ELISA kitHEMGN ELISA kitEDAG ELISA kitNDR ELISA kitPRO1037 ELISA kitPRO1620 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance