• Human HCII (Heparin Cofactor II) Sandwich ELISA Kit (STJE0009405)

Human HCII (Heparin Cofactor II) Sandwich ELISA Kit (STJE0009405)

SKU:
STJE0009405

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.067ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This HCII Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: SERPIND1
Gene ID: 3053
Uniprot ID: HEP2_HUMAN
Sample Type: plasma.
Tissue Specificity Expressed predominantly in liver. Also present in plasma.
Post Translational Modifications Phosphorylated by FAM20C in the extracellular medium.
Function Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
Protein Name Heparin Cofactor 2
Heparin Cofactor Ii
Hc-Ii
Protease Inhibitor Leuserpin-2
Hls2
Serpin D1
Database Links Reactome: R-HSA-140837
Reactome: R-HSA-140875
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation
Alternative ELISA Names Heparin Cofactor 2 ELISA kit
Heparin Cofactor Ii ELISA kit
Hc-Ii ELISA kit
Protease Inhibitor Leuserpin-2 ELISA kit
Hls2 ELISA kit
Serpin D1 ELISA kit
SERPIND1 ELISA kit
HCF2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance