• Human GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2C) Sandwich ELISA Kit Ready-To-Use (STJE0015689)

Human GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2C) Sandwich ELISA Kit Ready-To-Use (STJE0015689)

SKU:
STJE0015689

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.118ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This GRIN2C Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: GRIN2C
Gene ID: 2905
Uniprot ID: NMDE3_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Mainly expressed in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas.
Post Translational Modifications
Function Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable). Plays a role in regulating the balance between excitatory and inhibitory activity of pyramidal neurons in the prefrontal cortex. Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning.
Protein Name Glutamate Receptor Ionotropic - Nmda 2c
Glun2c
Glutamate Nmda Receptor Subunit Epsilon-3
N-Methyl D-Aspartate Receptor Subtype 2c
Nmdar2c
Nr2c
Database Links Reactome: R-HSA-438066
Reactome: R-HSA-6794361
Reactome: R-HSA-8849932
Reactome: R-HSA-9609736
Reactome: R-HSA-9617324
Reactome: R-HSA-9620244
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Postsynaptic Cell Membrane
Alternative ELISA Names Glutamate Receptor Ionotropic - Nmda 2c ELISA kit
Glun2c ELISA kit
Glutamate Nmda Receptor Subunit Epsilon-3 ELISA kit
N-Methyl D-Aspartate Receptor Subtype 2c ELISA kit
Nmdar2c ELISA kit
Nr2c ELISA kit
GRIN2C ELISA kit
NMDAR2C ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance