| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.054ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This GPIHBP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
GPIHBP1 |
| Gene ID: |
338328 |
| Uniprot ID: |
HDBP1_HUMAN |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Glycosylation of Asn-78 is critical for cell surface localization. Sulfation of a Tyr in the N-terminal acidic region increases the affinity for LPL. |
| Function | Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries. Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries. Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding. Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis. Binds chylomicrons and phospholipid particles that contain APOA5. Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL. |
| Protein Name | Glycosylphosphatidylinositol-Anchored High Density Lipoprotein-Binding Protein 1Gpi-Hbp1Gpi-Anchored Hdl-Binding Protein 1High Density Lipoprotein-Binding Protein 1 |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-8963889Reactome: R-HSA-8963901Reactome: R-HSA-975634 |
| Cellular Localisation | Apical Cell MembraneLipid-AnchorGpi-AnchorBasolateral Cell MembraneCell Membrane |
| Alternative ELISA Names | Glycosylphosphatidylinositol-Anchored High Density Lipoprotein-Binding Protein 1 ELISA kitGpi-Hbp1 ELISA kitGpi-Anchored Hdl-Binding Protein 1 ELISA kitHigh Density Lipoprotein-Binding Protein 1 ELISA kitGPIHBP1 ELISA kitHBP1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
