• Human GOD (Glucose Oxidase) Sandwich ELISA Kit (STJE0009235)

Human GOD (Glucose Oxidase) Sandwich ELISA Kit (STJE0009235)

SKU:
STJE0009235

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.113ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This GOD Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: HAO1
Gene ID: 54363
Uniprot ID: HAOX1_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Highly expressed in liver.
Post Translational Modifications
Function Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate. The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine.this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumulate, may be metabolized to oxalate with formation of kidney stones. Can also catalyze the oxidation of glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, albeit with much lower catalytic efficiency. Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2. Is not active on L-lactate and 2-hydroxybutanoate.
Protein Name 2-Hydroxyacid Oxidase 1
Haox1
Glycolate Oxidase
Go
Gox
Glyoxylate Oxidase
Database Links Reactome: R-HSA-389661
Reactome: R-HSA-9033241
Cellular Localisation Peroxisome Matrix
Alternative ELISA Names 2-Hydroxyacid Oxidase 1 ELISA kit
Haox1 ELISA kit
Glycolate Oxidase ELISA kit
Go ELISA kit
Gox ELISA kit
Glyoxylate Oxidase ELISA kit
HAO1 ELISA kit
GOX1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance